14182-64-0 Usage
Thioamide derivative
The compound contains a thione group (-CS-) which is a key structural feature of thioamides. Thioamides are known for their diverse biological activities and potential as pharmaceutical agents.
Morpholine ring
The compound contains a morpholine ring (a five-membered ring with two oxygen atoms and one nitrogen atom) which is known to possess a wide range of biological activities, including antifungal, antibacterial, and antiviral properties.
Ethylphenyl group
The compound contains an ethylphenyl group (a phenyl ring attached to an ethyl group) which may contribute to its biological activity. Alkylphenyl groups are commonly found in drug molecules due to their favorable pharmacokinetic properties.
Building block for organic synthesis
The compound is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various molecules.
Potential applications in medicinal chemistry
The chemical structure of 2-(4-ethylphenyl)-1-(morpholin-4-yl)ethanethione suggests potential applications in medicinal chemistry and pharmaceutical research due to its thioamide group, morpholine ring, and ethylphenyl group.
Check Digit Verification of cas no
The CAS Registry Mumber 14182-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,8 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 14182-64:
(7*1)+(6*4)+(5*1)+(4*8)+(3*2)+(2*6)+(1*4)=90
90 % 10 = 0
So 14182-64-0 is a valid CAS Registry Number.
14182-64-0Relevant articles and documents
Willgerodt-kindler's microwave-enhanced synthesis of thioamide derivatives
Poupaert, Jacques H.,Duarte, Sandro,Colacino, Evelina,Depreux, Patrick,McCurdy, Christopher R.,Lambert, Didier L.
, p. 1959 - 1973 (2007/10/03)
The Willgerodt-Kindler reaction was applied to a series of aromatic aldehydes and ketones. The reactions were performed in a dipolar aprotic solvent (mainly DMF) in the presence of a base catalyst (4-methylmorpholine) and utilized microwave (mw) irradiation. The pulsed mw technique rather than the continuous irradiation was preferred because it limited side reactions and hydrogen sulfide production. While not always superior to the thermal activation of the reaction, the procedure involving repetitive short pulses of microwave irradiation was found to be faster and result in consistently cleaner products. The technique can be easily applied in a fast parallel synthesis process.
