1418203-57-2

Basic information

• Product Name: 5-(2-bromophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline
• Synonyms: 5-(2-bromophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline
• CAS NO: 1418203-57-2
• Molecular Weight: 328.211
• Mol File: 1418203-57-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(2-bromophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-bromophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline(1418203-57-2)
• EPA Substance Registry System: 5-(2-bromophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline(1418203-57-2)

Safety Data

• Hazardous Substances Data: 1418203-57-2(Hazardous Substances Data)

Upstream product

• 1885-29-6 anthranilic acid nitrile 

Downstream Products

• 1418203-47-0 5-(2-bromophenyl)imidazo[1,2-c]quinazoline 
• 1418203-52-7 5-(2-bromophenyl)-2,3-dihydroimidazo[1,2-c]quinazoline 

Relevant articles and documents

An expedient synthesis of 5-substituted imidazo[1,2-c]quinazolines

An efficient three-step synthesis of 5-substituted 2,3-dihydroimidazo[1,2- c]quinazolines and imidazo[1,2-c]quinazolines was elaborated. 2-(2-Aminophenyl)-4,5-dihydro-1H-imidazole, prepared by phosphorus pentasulfide catalyzed condensation of 2-aminobenzonitrile with ethylenediamine, smoothly reacted with aldehydes to give the corresponding 2,3,5,6-tetrahydroimidazo[1,2- c]quinazolines. The CH-NH fragments of the latter were subjected to selective oxidative dehydrogenation with one equivalent of potassium permanganate on silica gel to give 2,3-dihydroimidazo[1,2-c]quinazolines. With two equivalents of potassium permanganate on silica gel, a one-pot exhaustive dehydrogenation to imidazo[1,2-c]quinazolines was accomplished. Georg Thieme Verlag KG · Stuttgart · New York.