141821-03-6

Basic information

• Product Name: (4-methylpenta-1,2-dien-1-yl)benzene
• Synonyms: (4-methylpenta-1,2-dien-1-yl)benzene
• CAS NO: 141821-03-6
• Molecular Weight: 158.243
• Mol File: 141821-03-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (4-methylpenta-1,2-dien-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methylpenta-1,2-dien-1-yl)benzene(141821-03-6)
• EPA Substance Registry System: (4-methylpenta-1,2-dien-1-yl)benzene(141821-03-6)

Safety Data

• Hazardous Substances Data: 141821-03-6(Hazardous Substances Data)

Upstream product

• 7154-75-8 4-methylpentyne 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 1220698-67-8 4-methyl-1-phenyl-1-pentyn-3-yl formate 
• 20208-71-3 4-methyl-N'-(2-methylpropylidene)benzenesulfonohydrazide 
• 536-74-3 phenylacetylene 
• 22174-62-5 (3-methoxy-4-methylpent-1-ynyl)benzene 
• 10575-81-2 1-bromo-4-methyl-1,2-pentadiene 
• 920-39-8 isopropylmagnesium bromide 
• 122044-10-4 Methanesulfinic acid (R)-1-phenyl-prop-2-ynyl ester 
• 591-51-5 phenyllithium 

Downstream Products

• 1134643-73-4 (E)-1,2-dimethyl-3-(4-methyl-1-phenylpent-2-enyl)-1H-indole 
• 1283231-61-7 (Z)-4,4,5,5-tetramethyl-2-(4-methyl-1-phenylpent-1-en-2-yl)-1,3,2-dioxaborolane 
• 1173936-86-1 (E)-2-isopropyl-1-(2-(methylthio)phenyl)-4-phenylbut-3-en-1-one 

Relevant articles and documents

Copper-Catalyzed 1,1-Boroalkylation of Terminal Alkynes: Access to Alkenylboronates via a Three-Component Reaction

A copper-catalyzed three-component reaction of terminal alkynes, diazo compounds, and B2pin2 to prepare trisubstituted alkenylboronates has been developed. This difunctionalization of alkynes selectively occurs at the terminal carbon atom and proceeds via

SAMDI Mass Spectrometry-Enabled High-Throughput Optimization of a Traceless Petasis Reaction

Development of the self-assembled monolayer/MALDI mass spectrometry (SAMDI) platform to enable a high-throughput optimization of a traceless Petasis reaction is described. More than 1800 unique reactions were conducted simultaneously on an array of self-assembled monolayers of alkanethiolates on gold to arrive at optimized conditions, which were then successfully transferred to the solution phase. The utility of this reaction was validated by the efficient synthesis of a variety of di- and trisubstituted allenes.

Some synthetic applications of vinylphosphane oxides

Vinylphosphane oxides have been used as Michael acceptors for the diastereoselective synthesis of anti α-functionalized-β-silylated phosphane oxides and β-stannyl-, β-phenylthio- or β-phosphanyl phosphane oxides. Although the utility of these substrates as dipolarophiles was more limited, we have obtained a mixture of 3- and 4-phosphanylpyrazoles in which the latter is the major regioisomer, by 1,3-cycloaddition with N-phenylsydnone. Moreover, vinylphosphane oxides reacted with aldehydes in the presence of LDA by a Baylis-Hillman type reaction, leading to (E)-β-hydroxyphosphane oxides, which were readily converted in allenes. It is noteworthy that the application of this methodology to silylated substrates has permitted us to synthesize an interesting and more versatile silylallene.