1418317-22-2Relevant articles and documents
Iron-mediated decarboxylative trifluoromethylation of α,β- unsaturated carboxylic acids with trifluoromethanesulfinate
Patra, Tuhin,Deb, Arghya,Manna, Srimanta,Sharma, Upendra,Maiti, Debabrata
, p. 5247 - 5250 (2013)
A sustainable FeCl3-mediated method has been developed for the decarboxylative trifluoromethylation of α,β-unsaturated carboxylic acids by using NaSO2CF3 as an economic and stable CF 3 source. The reaction proceeds under mild condition and tolerates various functional groups. Advantageously, this method does not require an inert atmosphere and proceeds well in air at ambient temperature. A sustainable FeCl3-mediated method has been developed for the decarboxylative trifluoromethylation of α,β-unsaturated carboxylic acids by using NaSO2CF3 as an economic and stable CF3 source. This method does not require an inert atmosphere and proceeds well in air at ambient temperature. Copyright
Exploring the Structure and Performance of Cd–Chalcogenide Photocatalysts in Selective Trifluoromethylation
Muralirajan, Krishnamoorthy,Kancherla, Rajesh,Bau, Jeremy A.,Taksande, Mayur Rahul,Qureshi, Muhammad,Takanabe, Kazuhiro,Rueping, Magnus
, p. 14772 - 14780 (2021/12/09)
The field of heterogeneous photoredox catalysis has grown substantially and impacted organic synthesis because of the affordability and reusability of catalysts. This study reports radical trifluoromethylation with Cd–chalcogenide semiconductors. Cd semiconductors, particularly CdSe, are readily available, commercial, visible-light-responsive, heterogeneous photocatalysts. The potential of readily available Cd semiconductors, particularly CdSe, is confirmed by their increased photocatalytic activity toward trifluoromethylation with various substrates, such as (hetero)arenes and vinylic amides/acids, via addition, cyclization, and decarboxylation under visible light. The economic significance of this strategy is also highlighted through the scalable synthesis of biologically active molecules followed by catalyst reuse. Moreover, these catalysts are relatively inexpensive compared with transition metal-based homogeneous photocatalysts, presently used in organic synthesis.
Metal-free radical trifluoromethylation of β-nitroalkenes through visible-light photoredox catalysis
Midya, Siba P.,Rana, Jagannath,Abraham, Thomas,Aswin, Bhaskaran,Balaraman, Ekambaram
, p. 6760 - 6763 (2017/07/10)
A catalytic method for functional group interconversion is immensely important in modern sciences. Here, we report an efficient catalytic conversion of nitroalkenes to highly stereoselective 1-trifluoromethylalkenes at room temperature. This unprecedented metal-free photocatalytic strategy is simple and operates under visible-light irradiation using the commercially available CF3 source.