141834-87-9

Upstream product

• 6953-22-6 5-benzyloxyindole-3-carboxaldehyde 
• 73391-97-6 N-methyl-N-2-phenylethyl-2-bromoacetamide 
• 589-08-2 N-Methyl-N-phenethylamine 

Downstream Products

• 141834-94-8 (E)-3-{5-Benzyloxy-1-[(methyl-phenethyl-carbamoyl)-methyl]-1H-indol-3-yl}-acrylic acid ethyl ester 
• 141863-33-4 (2E,4E)-5-{5-Benzyloxy-1-[(methyl-phenethyl-carbamoyl)-methyl]-1H-indol-3-yl}-penta-2,4-dienoic acid ethyl ester 
• 141834-97-1 N-methyl-N-phenethyl-2[-5-benzyloxy-3-(2-carbethoxyethyl)indol-1-yl]acetamide 

Relevant academic research and scientific papers

Structure-activity relationships study of two series of leukotriene B4 antagonists: Novel indolyl and naphthyl compounds substituted with a 2- [methyl(2-phenethyl)amino]-2-oxoethyl side chain

N-Methyl-N-phenethylphenylacetamide has been reported to be a key binding domain to LTB4 receptors. Here we describe the synthesis and structure-activity relationship (SAR) studies of two new series of LTB4 receptor antagonists in wh

SUBSTITUTED NAPHTHYLENE COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY

This invention relates to bicyclic aryl compounds having selective LTB. sub.4 antagonist properties and comprising an amido substituent, a substituent group having a terminal carboxylic acid or derivative thereof and a lipophilic substituent, and to metho