141857-29-6

Basic information

• Product Name: 4-thioanisyl-2-biphenylyl-3-hydroxypropionic acid
• Synonyms: 4-thioanisyl-2-biphenylyl-3-hydroxypropionic acid
• CAS NO: 141857-29-6
• Molecular Formula: C₂₂H₂₀O₃S
• Molecular Weight: 0
• Mol File: 141857-29-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 570.6°Cat760mmHg
• Flash Point: 298.9°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 7.4E-14mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 4-thioanisyl-2-biphenylyl-3-hydroxypropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-thioanisyl-2-biphenylyl-3-hydroxypropionic acid(141857-29-6)
• EPA Substance Registry System: 4-thioanisyl-2-biphenylyl-3-hydroxypropionic acid(141857-29-6)

Safety Data

• Hazardous Substances Data: 141857-29-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H20O3S/c1-26-18-13-11-17(12-14-18)25-22(24)21(15-23)20-10-6-5-9-19(20)16-7-3-2-4-8-16/h2-14,21,23H,15H2,1H3

Upstream product

• 5728-52-9 (4-biphenylyl)acetic acid 
• 3446-89-7 4-(Methylthio)benzaldehyde 

Downstream Products

• 141857-30-9 2-Biphenyl-4-yl-3-hydroxy-3-(4-methylsulfanyl-phenyl)-propionic acid methyl ester 
• 141857-30-9 2-Biphenyl-4-yl-3-hydroxy-3-(4-methylsulfanyl-phenyl)-propionic acid methyl ester 

Relevant articles and documents

Nonsteroidal antiinflammatory agents. Part 21: Optically active stereoisomers of p-trifluoromethylphenyl- and p-thioanisyl-biphenylyl-hydroxypropionic acids

The synthesis, diastereomeric separation, assignment to erythro- and threo-configuration by 1HNMR, and optical resolution of 3-(p-trifluoromethyl-phenyl)- and (p-thioanisyl)-2-biphenylyl-3-hydroxypropionic acids are described. The enantiomers were submitted to a preliminary assay to determine antiinflammatory activity.