141860-87-9Relevant academic research and scientific papers
SYNTHESES OF NEW 4-TRIFLUOROMETHYLATED 1,3-OXAZIN-6-ONES FROM THE ENAMINE OF ETHYL TRIFLUOROACETOACETATE
Decock-Plancquaert, Marie-Aimee,Evariste, Francois,Guillot, Nadine,Janousek, Zdenek,Maliverney, Christian,et al.
, p. 313 - 322 (2007/10/02)
New 4-trifluoromethyl-1,3-oxazin-6-ones have been prepared in excellent yields form ethyl 3-amino-4,4,4-trifluorocrotonate (ATFC) by two original procedures: reaction of ATFC with phosgeniminium chlorides to give 2-dialkylamino-4-trifluoromethyl-1,3-oxazin-6-ones, or action of chlorinating agents on N-acyl ATFC.The reactivity of ATFC in these reactions is compared with non-fluorinated analogs.
