141865-60-3Relevant academic research and scientific papers
Synthesis of branched nucleosides closely related to AZT, involving SN2′ opening of anhydronucleosides
Czernecki, Stanislas,Ezzitouni, Abdallah
, p. 315 - 318 (1993)
Three 2′,3′-unsaturated pyrimidine nucleosides, bearing an azido-methyl group at 2′ or 3′ were synthesized as potential anti-HIV agents. The key step involves an SN2′ opening of 2,2′ or 2,3′-anhydronucleosides by azide ion.
