141903-33-5

Upstream product

• 1035804-85-3 3,6-bis(ethoxycarbonyl)-2,2-diethoxy-4-methyl-1-(methylsulfonyl)-1,2,3,4-tetrahydropyridine 
• 141903-29-9 6-Ethoxy-4-(3-oxo-cyclopentylmethyl)-pyridine-2,5-dicarboxylic acid diethyl ester 
• 141903-28-8 1-ethoxy-3-(ethoxycarbonyl)-5,5a,7,8-tetrahydro-9-hydroxy-6H-cyclopentisoquinolin-8-one 
• 141903-26-6 3,6-bis(ethoxycarbonyl)-2-ethoxy-4-methylpyridine 
• 100-39-0 benzyl bromide 
• 141903-31-3 1-ethoxy-3-(ethoxycarbonyl)-7,8-dihydro-9-hydroxy-6H-cyclopentisoquinolin-8-one 

Downstream Products

• 80455-68-1 fredericamycin A 
• 1026928-31-3 C₅₁H₄₉NO₁₁ 
• 1026535-33-0 5,8-bis(methoxymethoxy)-9,9'-bis(phenylmethoxy)-6',7'-dihydro-4,6-dimethoxy-1'-ethoxy-3-hydroxy-3'-(1,3-pentadienyl)spiro<2H-benzindene-2,8'-8'H-cyclopentisoquinolin>-1(3H)-one 
• 1027210-63-4 5,8-bis(methoxymethoxy)-1,7-dimethoxy-2-(1-hydroxymethyl)-4-(phenylmethoxy)-3-<1-<1'-ethoxy-3'-(1,3-pentadienyl)-9'-(phenylmethoxy)-6',7'-dihydro-8'H-cyclopentisoquinolinyl>-1-(hydroxymethyl)>naphthalene 
• 172268-84-7 9-(benzyloxy)-8-cyano-1-ethoxy-3-(ethoxycarbonyl)-7,8-dihydro-6H-cyclopentisoquinoline 
• 172268-92-7 9-(benzyloxy)-8-cyano-1-ethoxy-3-((tert-butyldimethylsilyloxy)methyl)-7,8-dihydro-6H-cyclopentisoquinoline 
• 172268-85-8 9-(benzyloxy)-8-cyano-1-ethoxy-3-(hydroxymethyl)-7,8-dihydro-6H-cyclopentisoquinoline 
• 172268-86-9 9-(benzyloxy)-8-cyano-1-ethoxy-7,8-dihydro-6H-cyclopentisoquinoline-3-carboxaldehyde 
• 172269-15-7 9-(benzyloxy)-8-cyano-1-ethoxy-7,8-dihydro-6H-cyclopentisoquinoline-3-carboxylic acid 

Relevant academic research and scientific papers

Total synthesis of natural and ent-fredericamycin A

A total synthesis of both enantiomers of the potent antitumor-antibiotic fredericamycin A is detailed based on a room temperature inverse electron demand Diels-Alder reaction of a N-sulfonyl-1-aza-1,3-butadiene for assemblage of a pyridone F ring precurso

A Concise Synthesis of Fredericamycin A DEF Ring System: Cycloaddition reactions of 1-Aza-1,3-butadienes

A concise four-step synthesis of fredericamycin A DEF ring system is detailed based on the LUMOdiene-controlled Diels-Alder reaction of N-sulfonyl-1-azadiene 3 for introduction of the pyridone F ring.