1419101-66-8

Basic information

• Product Name: methyl 2-methyl-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-carboxylate
• Synonyms: methyl 2-methyl-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-carboxylate
• CAS NO: 1419101-66-8
• Molecular Weight: 305.331
• Mol File: 1419101-66-8.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-methyl-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-methyl-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-carboxylate(1419101-66-8)
• EPA Substance Registry System: methyl 2-methyl-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-carboxylate(1419101-66-8)

Safety Data

• Hazardous Substances Data: 1419101-66-8(Hazardous Substances Data)

Upstream product

• 51490-01-8 1-(3,4,5-trimethoxyphenyl)-2-bromoethanone 
• 105-45-3 acetoacetic acid methyl ester 
• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 14205-39-1 methyl 3-aminocrotonate 
• 7702-09-2 2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone 

Relevant articles and documents

Green multicomponent reaction for synthesis of trisubstituted pyrroles in ionic liquid [bmim]BF4

2,4,5-Trisubstituted pyrrole derivatives were efficiently synthesized by one-pot condensation of 1,3-diones, α-bromoacetophenones, and ammonium acetate in ionic liquid [bmim]BF4. The new synthetic method offers multisubstituted pyrroles with th

I2-DMSO promoted metal free oxidative cyclization for the synthesis of substituted Indoles and pyrroles

A series of di substituted indole and tri substituted pyrrole derivatives were synthesized efficiently by using I2/K2CO3 in DMSO. The novel synthesis method offers the advantage of mild reaction conditions, operational simplicity, higher yields. The method is functional group tolerant and provides quick access to medicinally significant compounds in moderate to high yields.

Microwave-assisted facile synthesis of trisubstituted pyrrole derivatives

We report efficient synthesis of pyrrole derivatives by use of microwave irradiation. Quantitative yields were obtained in short reaction times. Low yields of product were obtained from alicyclic amino unsaturated ketone derivatives; higher yields were ob

Cu(OTf)2-catalyzed synthesis of 2,3-disubstituted indoles and 2,4,5-trisubstituted pyrroles from α-diazoketones

A novel method has been devised for the synthesis of 2,4,5-trisubstituted pyrrole derivatives through the coupling of α-diazoketones with β-enaminoketones and esters using 10 mol % of Cu(OTf)2. A wide range of 2,3-disubstituted indole derivatives were also prepared from α-diazoketones and 2-aminoaryl or alkyl ketones. The synthetic versatility of this approach has been exemplified in the formal synthesis of homofascaplysin C.