7702-09-2

Basic information

• Product Name: [2-oxo-2-(3,4,5-trimethoxyphenyl)ethylidene]diazenium
• CAS NO: 7702-09-2
• Molecular Formula: C₁₁H₁₂N₂O₄
• Molecular Weight: 237.2314
• Mol File: 7702-09-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: [2-oxo-2-(3,4,5-trimethoxyphenyl)ethylidene]diazenium(CAS DataBase Reference)
• NIST Chemistry Reference: [2-oxo-2-(3,4,5-trimethoxyphenyl)ethylidene]diazenium(7702-09-2)
• EPA Substance Registry System: [2-oxo-2-(3,4,5-trimethoxyphenyl)ethylidene]diazenium(7702-09-2)

Safety Data

• Hazardous Substances Data: 7702-09-2(Hazardous Substances Data)

Usage

General Description

[2-oxo-2-(3,4,5-trimethoxyphenyl)ethylidene]diazenium is a chemical compound with the molecular formula C12H14N2O5. It is a diazeniumdiolate, which is a class of compounds that contain a structurally unusual N2O2 four-membered ring that is formed by the conversion of nitric oxide to its anion. This particular compound contains a 2-oxo-2-(3,4,5-trimethoxyphenyl)ethylidene group, which is a functional group consisting of a ketone and an aromatic ring with three methoxy substituents. It is important to note that diazeniumdiolates are known for their potential use as nitric oxide donors, which makes them potentially important in the field of medicine for their vasodilatory and anti-inflammatory properties.

Upstream product

• 186581-53-3 diazomethane 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 93199-59-8 1,3-di-(3,4,5-trimethoxyphenyl)-1,3-propanedione 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 118-41-2 Eudesmic acid 

Downstream Products

• 2989-06-2 methyl 2-(3,4,5-trimethoxyphenyl)acetate 
• 91248-14-5 2-(3,4,5-trimethoxyphenyl)acetamide 
• 1261073-29-3 7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline 
• 1261073-28-2 C₁₈H₁₈N₂O₃ 
• 1419101-56-6 (5,6-dimethoxy-3-methyl-1H-indol-2-yl-)(3,4,5-trimethoxyphenyl)methanone 
• 1419101-66-8 methyl 2-methyl-5-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-carboxylate 
• 1419101-57-7 (5-chloro-3-phenyl-1H-indol-2-yl)(3,4,5-trimethoxyphenyl)methanone 
• 909724-13-6 dithiocarbonic acid O-ethyl ester S-[2-oxo-2-(3,4,5-trimethoxyphenyl)-ethyl] ester 
• 4838-96-4 N-methyl-3,4,5-trimethoxyphenethylamine 

Relevant articles and documents

Preparation method for 2-diazonium-1-alkyl ketone compound

The invention provides a preparation method for a 2-diazonium-1-alkyl ketone compound. The preparation method is characterized in that a beta-dicarbonyl compound, p-toluenesulfonyl azide and methylamine are taken as raw materials, and a catalyst and alkali are not needed under a room-temperature condition, so that the 2-diazonium-1-alkyl ketone compound can be quickly and efficiently generated. Compared with the prior art, the preparation method is safe, simple and convenient to operate, and avoids a diazotization step which is dangerous to operate. The preparation method is gentle in reaction condition, is quick and efficient, and provides a brand-new and more convenient method for quickly and efficiently preparing an alpha-diazonium-alkyl ketone compound, and the method can be applied to the fields such as the chemical pharmaceuticals, the biological field and the material field.

An efficient PEG-400 mediated catalyst free green synthesis of 2-amino-thiazoles from α-diazoketones and thiourea

A simple and efficient method has been developed for the synthesis of 2-aminothiazoles from α-diazoketones using PEG-400 solvent system. This novel synthetic approach involves the reaction between thiourea and α-diazoketones in PEG-400 at 100 °C to yield the corresponding 2-aminothiazoles in good yields. The method is simple, rapid and generates thiazole derivatives in excellent yields without the use of any catalysts. This green protocol can be utilized for fast synthesis of various 2-aminothiazoles in good yields. [Figure not available: see fulltext.]

First example of the coupling of α-diazoketones with thiourea: a novel route for the synthesis of 2-aminothiazoles

α-Diazoketones undergo smooth coupling with thiourea in the presence of 10 mol % of copper(II) triflate to produce the corresponding 2-aminothiazoles in excellent yields with high selectivity. The use of copper(II) triflate makes this method simple, convenient and practical. This method works well with both aryl and alkyl diazoketones to furnish a wide range of 2-aminothiazoles.