1419178-84-9Relevant academic research and scientific papers
Toward the synthesis of phomoidride D
Murphy, Graham K.,Shirahata, Tatsuya,Hama, Naoto,Bedermann, Aaron,Dong, Ping,McMahon, Travis C.,Twenter, Barry M.,Spiegel, David A.,McDonald, Ivar M.,Taniguchi, Nobuaki,Inoue, Munenori,Wood, John L.
, p. 477 - 489 (2013/03/14)
An efficient and highly stereoselective approach toward the phomoidride family of natural products is described. The carbocyclic core structure was assembled using a tandem phenolic oxidation/Diels-Alder cycloaddition and a tandem 5-exo-trig/5-exo-trig radical cyclization to deliver an isotwistane intermediate that, upon a late-stage xanthate-initiated Grob fragmentation, furnishes the requisite bicyclo[4.3.1]decene.
