141925-85-1

Upstream product

• 2389-60-8 Z-Lys(Boc)-OH 
• 530-62-1 1,1'-carbonyldiimidazole 
• 2418-95-3 (S)-2-amino-6-(tert-butoxycarbonylamino)hexanoic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 167275-72-1 (S)-4-Benzyloxycarbonylamino-8-tert-butoxycarbonylamino-3-oxo-octanoic acid ethyl ester 
• 122477-82-1 tert-butyl-N-[(5S)-5-(benzyloxycarbonylamino)-6-hydroxyhexyl]carbamate 
• 167275-73-2 (3R,4S)-4-Benzyloxycarbonylamino-8-tert-butoxycarbonylamino-3-hydroxy-octanoic acid ethyl ester 

Relevant academic research and scientific papers

An efficient synthesis of alterobactin A; a super siderophore of marine origin

Alterobactin A (1), a cyclic depsipeptide and a super siderophore isolated from an open-ocean bacterium, was efficiently synthesized for the first time by a convergent manner with the maximum protection of various functional groups.

CHIRAL CYCLEN COMPOUNDS AND THEIR USES

The present invention relates to the preparation of a series of chiral DOTA, D03A, D02A, DO1A, cyclen and their metal complexes, which display properties superior to those of previous DOTA- based compounds, and hence are potentially valuable as a platform for diagnostic applications. The chiral DOTAs reveal a high abundance of twisted square antiprism (TSA) geometry favoring them to be used as potential MRI contrast agents, whereas their rapid labelling properties at mild conditions make them excellent candidates for use as radiometal chelators.