141936-98-3Relevant academic research and scientific papers
Synthesis of the Tricyclic Nucleus of the Alkaloid Stemofoline: X-Ray Crystal Structure of (4RS,5RS,7SR,10RS)-10-Butyl-5-hydroxy-1-azatricyclo4,10>decan-2-one
Beddoes, Roy L.,Davies, Michael P. H.,Thomas, Eric J.
, p. 538 - 540 (1992)
The tricyclic lactams 20 and 21 have been synthesized using iminium ion cyclisations and formation of the third ring via halogen metal exchange; oxidation of the lactam 22 using lead(IV) acetate gave the tetracyclic ether 27 regioselectively.
Synthetic approaches to the polycyclic alkaloid stemofoline
Baylis, Alison M.,Davies, Michael. P. H.,Thomas, Eric J.
, p. 3139 - 3155 (2008/04/01)
Preliminary studies of a synthetic approach to the alkaloid stemofoline 1 are reported. Stereoselective cyclisation of the ketoester 14 gave the 1-butyl-2,8-bis(methoxycarbonyl)-8-azabicyclo[3.2.1]octane 21 in which the 2-methoxycarbonyl group is in the a
