141946-39-6

Basic information

• Product Name: 5-Methoxy-3-[1-(6-methyl-pyridin-2-yl)-meth-(E)-ylidene]-1,3-dihydro-indol-2-one
• Synonyms: 5-Methoxy-3-[1-(6-methyl-pyridin-2-yl)-meth-(E)-ylidene]-1,3-dihydro-indol-2-one
• CAS NO: 141946-39-6
• Molecular Weight: 266.299
• Mol File: 141946-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Methoxy-3-[1-(6-methyl-pyridin-2-yl)-meth-(E)-ylidene]-1,3-dihydro-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxy-3-[1-(6-methyl-pyridin-2-yl)-meth-(E)-ylidene]-1,3-dihydro-indol-2-one(141946-39-6)
• EPA Substance Registry System: 5-Methoxy-3-[1-(6-methyl-pyridin-2-yl)-meth-(E)-ylidene]-1,3-dihydro-indol-2-one(141946-39-6)

Safety Data

• Hazardous Substances Data: 141946-39-6(Hazardous Substances Data)

Upstream product

• 1122-72-1 6-methyl-2-pyridinecarboxaldehyde 
• 7699-18-5 5-methoxyindolin-2-one 

Relevant articles and documents

Synthesis and cardiotonic activity of pyridylmethylene-2-indolinones

The title compounds were prepared by reaction of 3 2-indolinones with 3 different pyridinecarboxaldehydes. In one case (7b) it was possible to isolate and characterize both the E and Z isomers. In the other cases (except 5b) the E isomer was largely predominant or the only one present. The pharmacological activity of E-7b was not significantly different from that of Z-7b. Compound 6b, arising from the reaction of 5-methoxy-2-indolinone with 3-pyridinecarboxaldehyde, was significantly more active than the other compounds prepared.