141971-67-7Relevant academic research and scientific papers
"SAFETY-CATCH" PROTECTING GROUPS IN PEPTIDE SYNTHESIS
Patek, Marcel,Lebl, Michal
, p. 508 - 524 (2007/10/02)
A new benzhydryl-type protective groups for amides based on the concept of converting a stable protecting group into a labile one (safety-catch principle) are described.The p-substituted benzhydrylamine derivatives III(a, b), IV(a, b) are shown to be labi
A SAFETY-CATCH TYPE OF AMIDE PROTECTING GROUP
Patek, Marcel,Lebl, Michal
, p. 5209 - 5212 (2007/10/02)
p-Substituted benzhydrylamine derivatives 1-4 were synthesized and evaluated for their lability towards various acids.The pair 2 and 4 seems to be suitable for peptide synthesis using the base labile Fmoc- and/or acid labile Boc-strategy.
