141989-45-9Relevant academic research and scientific papers
INVESTIGATIONS OF 2-SUBSTITUTED IMIDAZOLES. 2. SYNTHESIS AND ELECTROPHILIC SUBSTITUTION OF 1-METHYL-2-(THIENYL-2)IMIDAZOLE. A CONVENIENT METHOD OF METHYLATION OF 2-R-IMIDAZOLES
Stoyanov, V. M.,El'chaninov, M. M.,Pozharskii, A. F.
, p. 1140 - 1144 (2007/10/02)
We have synthesized 2-(thienyl-2)imidazole and its N-methyl derivative.The latter product was obtained by nitration, bromination, acylation, and formylation, occurring as a rule on the thiophene ring.A general method for methylating 2-R-imidazoles with methyl iodide KOH-dimethoxy ethane is proposed.
