141993-75-1Relevant academic research and scientific papers
Fluoroquinolones from imidoylketenes and iminopropadienones, RN≤C≤C≤C≤O
Fulloon, Belinda E.,Wentrup, Curt
experimental part, p. 115 - 120 (2009/08/15)
3-Fluoro-, 4-fluoro-, and 2,3,4-trifluorophenyliminopropadienones have been generated by flash vacuum thermolysis (FVT) of 5-[(fluoroarylamino) methoxymethylene]-2,2-dimethyldioxan-4,6-dione (Meldrum's acid) derivatives. Their reaction with methanol affor
Synthesis of 2-amino-1,4-dihydro-4-quinolinones and diaminomethylene Meldrum's acids derivatives as potential potassium channel openers
Erb, Benedicte,Rigo, Benoit,Pirotte, Bernard,Couturier, Daniel
, p. 15 - 28 (2007/10/03)
Starting from 5-bismethylthiomethylene Meldrum's acid, the synthesis of 5-diaminomethylene Meldrum's acids and 2-aminoquinolone derivatives, structurally related to potassium channels openers pinacidil and diazoxide, is described.
