142010-18-2

Upstream product

• 142010-17-1 methyl (E)-3-(5′-methoxy-2′-nitrophenyl)acrylate 
• 292638-85-8 acrylic acid methyl ester 
• 191348-14-8 2-iodo-4-methoxylaniline 
• 20357-24-8 5-methoxy-2-nitro-benzaldehyde 
• 42454-06-8 2-nitro-5-hydroxybenzaldehyde 

Downstream Products

• 231296-73-4 methyl trans-5-methoxy-2-[(phenylsulfonyl)amino]cinnamate 
• 142010-15-9 Cyclohexyl-carbamic acid 1,3-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d][1,3]diazocin-8-yl ester 
• 125810-74-4 6-Methoxy-4-methoxycarbonylmethyl-2-oxo-1,2,3,4-tetrahydro-quinoline-3-carboxylic acid methyl ester 
• 125810-76-6 (6-Methoxy-1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-4-yl)-acetic acid methyl ester 
• 125810-75-5 (6-Methoxy-2-oxo-1,2,3,4-tetrahydro-quinolin-4-yl)-acetic acid methyl ester 
• 231293-65-5 methyl [2-(4-chlorobenzoyl)-5-methoxy-1H-indol-3-yl]acetate 
• 142010-19-3 3-[[2-[(methoxycarbonyl)ethenyl]-4-methoxyphenyl]amino]-3-oxopropanoic acid, ethyl ester 

Relevant academic research and scientific papers

Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines Using a One-Pot Multibond Forming Process

Rapid access to allylic trichloroacetimidates bearing a 2-allylaminoaryl group from readily available 2-iodoanilines combined with a one-pot multibond forming process has allowed the efficient synthesis of a series of 5-amino-2,5-dihydro-1H-benzo[b]azepin

Synthesis of 2-acylindole-3-acetic acids: A novel base-mediated indole synthesis

An efficient and expedient synthetic route to 2-acylindole-3-acetic acids is described. This work first demonstrates a one-pot room-temperature indole ring construction via the in situ generation of indoline intermediate.

2,3-substituted indole compounds as anti-inflammatory and analgesic agents

This invention provides a compound of the following formula: or the pharmaceutically acceptable salts thereof wherein Z is OH, C1-6 alkoxy, —NR2R3 or heterocycle; Q is selected from the following: (a) an optionally substituted phenyl, (b) an optionally substituted 6-membered monocyclic aromatic group containing one, two, three or four nitrogen atom(s), (c) an optionally substituted 5-membered monocyclic aromatic group containing one heteroatom selected from O, S and N and optionally containing one, two or three nitrogen atom(s) in addition to said heteroatom, (d) an optionally substituted C3-7 cycloalkyl and (e) an optionally substituted benzo-fuzed heterocycle; R1 is hydrogen, C1-4 alkyl or halo; R2 and R3 are independently hydrogen, OH, C1-4 alkoxy, C1-4 alkyl or C1-4 alkyl substituted with halo, OH, C1-4 alkoxy or CN; X is independently selected from H, halo, C1-4 alkyl, halo-substituted C1-4 alkyl, OH, C1-4 alkoxy, halo-substituted C1-4 alkoxy, C1-4 alkylthio, NO2, NH2, di-(C1-4 alkyl)amino and CN; and n is 0, 1, 2, 3 and 4.This invention also provides a pharmaceutical composition useful for the treatment of a medical condition in which prostaglandins are implicated as pathogens.

Bicycliccarbonyl indole compounds as anti-inflammatory/analgesic agents

This invention provides a compound of the following formula: or the pharmaceutically acceptable salts thereof wherein A is C1-6alkylene or —NR1—; Z is C(═L)R2, or SO2R3; U is CH or N; W and Y are inde

Transition metal complexes in organic synthesis, part 36. Cyclization of tricarbonyliron complexes by oxygen to 4a,9a-Dihydro-9H-carbazoles: Application to the synthesis of mukonine, mukonidine, and pyrido[3,2,1-jk]carbazoles

Aryl-substituted tricarbonyl(η4-cyclohexa-1,3-diene)iron complexes are oxidatively cyclized in protic medium in the air to tricarbonyliron-complexed 4a,9a-dihydro-9H-carbazoles. The method is applied to the total synthesis of mukonine and mukon

SYNTHESIS AND CARBAMOYLATION OF 1,2,3,4,5,6-HEXAHYDRO-1,3-DIMETHYL-2,6-METHANO-1,3-BENZODIAZOCIN-8-OL: BRIDGED ANALOGUES OF PHYSOSTIGMIN

The synthesis and carbamoylation of 2,6-methano-1,3-benzodiazocin-8-ol is described.A one pot silyl-aryl ether to carbamate transformation was developed.The compounds are analogues of the cholinesterase inhibitor physostigmin.