142011-18-5Relevant academic research and scientific papers
Oxidative Desulfurization-Fluorination of Methyl Arenedithiocarboxylates. A Convenient Synthesis of Trifluoromethylated Aromatic Compounds
Kuroboshi, Manabu,Hiyama, Tamejiro
, p. 827 - 830 (1992)
Trifluoromethyl-substituted aromatic compounds were obtained by oxidative desulfurization-fluorination reaction of methyl arenedithiocarboxylates using n-Bu4N+H2F3- and 1,3-dibromo-5,5-dimethylhydantoin (DBH).Use of N-bromosuccinimide or N-iodosuccinimide instead of DBH afforded difluoro(methylthio)methyl-substituted aromatics.
A facile synthesis of trifluoromethyl- and 3,3,3-trifluoropropenyl- substituted aromatic compounds by the oxidative desulfurization-fluorination of the corresponding carbodithioates
Furuta, Satoru,Kuroboshi, Manabu,Hiyama, Tamejiro
, p. 805 - 819 (2007/10/03)
Trifluoromethyl-substituted aromatic compounds were easily synthesized by the oxidative desulfurization-fluorination reaction of readily accessible methyl arenecarbodithioates using [n-Bu4N]H2F3 and 1,3-dibromo-5,5- dimethylhydantoin (DBH) under extremely mild conditions. Use of N- bromosuccinimide or N-iodosuccinimide instead of DBH afforded difluoro(methylthio)methyl-substituted aromatics. In a similar way, 3,3,3- trifluoropropenyl-substituted aromatic compounds were readily prepared from the corresponding α,β-unsaturated carbodithioates.
