Oxidative Desulfurization-Fluorination of Methyl Arenedithiocarboxylates. A Convenient Synthesis of Trifluoromethylated Aromatic Compounds

Article abstract of DOI:10.1246/cl.1992.827

Trifluoromethyl-substituted aromatic compounds were obtained by oxidative desulfurization-fluorination reaction of methyl arenedithiocarboxylates using n-Bu4N⁺H2F3^- and 1,3-dibromo-5,5-dimethylhydantoin (DBH).Use of N-bromosuccinimide or N-iodosuccinimide instead of DBH afforded difluoro(methylthio)methyl-substituted aromatics.