1420295-64-2

Basic information

• Product Name: 2-(4-bromophenyl)-3-(dimethoxymethyl)quinoxaline
• CAS NO: 1420295-64-2
• Molecular Weight: 359.222
• Mol File: 1420295-64-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-bromophenyl)-3-(dimethoxymethyl)quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-bromophenyl)-3-(dimethoxymethyl)quinoxaline(1420295-64-2)
• EPA Substance Registry System: 2-(4-bromophenyl)-3-(dimethoxymethyl)quinoxaline(1420295-64-2)

Safety Data

• Hazardous Substances Data: 1420295-64-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 5021-45-4 2-(4-bromophenyl)quinoxaline 

Relevant articles and documents

Multifold bond cleavage and formation between meoh and quinoxalines (or benzothiazoles): Synthesis of carbaldehyde dimethyl acetals

A K2S2O8-mediated direct cross-coupling of quinoxalines (or benzothiazoles) with methanol leading to 2-quinoxalinyl (or 2-benzothiazolyl) carbaldehyde dimethyl acetals has been achieved. 2-Quinoxalinyl carbaldehyde dimethyl acetals were readily converted into 2-quinoxalinyl carbaldehydes in good to excellent yields under acidic conditions. Preliminary mechanistic studies suggest that the reaction proceeds via multifold bond cleavage and formation between methanol and N-heterocycles involving a dioxygen-participated radical process. This method allows for the synthesis of a variety of 2-quinoxalinyl (or 2-benzothiazolyl) carbaldehyde dimethyl acetals directly via cross-coupling of simple N-heterocyclic C-H bond and methanol under aldehyde-, acid-, and transition-metal-free conditions.