14203-24-8

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-1,3-cyclopentanedione is used as a key building block for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-1,3-cyclopentanedione serves as an essential intermediate in the production of agrochemicals. Its incorporation aids in the formulation of effective pesticides and other agricultural products designed to enhance crop protection and yield.
Used in Research Laboratories:
2-Bromo-1,3-cyclopentanedione is utilized as a reagent in research laboratories. Its properties make it suitable for various experimental procedures and the exploration of new chemical reactions, thus fostering scientific discovery and innovation.
Used in Industrial Settings:
2-Bromo-1,3-cyclopentanedione also finds application in industrial settings as an intermediate in the synthesis of other organic compounds. Its versatility in organic synthesis processes is valuable for the production of a wide range of specialty chemicals and intermediates used across different industries.
Despite its limited commercial availability, 2-Bromo-1,3-cyclopentanedione holds significant value in both research and industrial applications, underpinning its importance in the development of new chemical entities and products.

Upstream product

• 3859-41-4 1,3-cyclopentadione 
• 14203-23-7 2-Acetyl-2-brom-cyclopentan-1,3-dion 
• 3294-60-8 phenyl(tribromomethyl)mercury(II) 
• 106-65-0 Dimethyl succinate 

Downstream Products

• 883195-36-6 N-(6-oxo-5,6-dihydro-4H-cyclopentathiazol-2-yl)-acetamide 
• 252235-51-1 acetic acid 2-bromo-3-[3-(toluene-4-sulfonyloxy)-propyl]-cyclopent-2-enyl ester 
• 252235-48-6 acetic acid 3-[3-(toluene-4-sulfonyloxy)-propyl]-cyclopent-2-enyl ester 
• 252235-50-0 4-toluenesulfonic acid 3-(2-bromo-3-oxo-cyclopent-1-enyl)-propyl ester 

Relevant academic research and scientific papers

TARGETED BIFUNCTIONAL DEGRADERS

The present invention provides, in one aspect, bifunctional compounds that can be used to promote or enhance degradation of certain circulating proteins. In another aspect, the present invention provides bifunctional compounds that can be used to promote or enhance degradation of certain autoantibodies. In certain embodiments, treatment or management of a disease and/or disorder requires degradation, removal, or reduction in concentration of the circulating protein or the autoantibody in the subject. Thus, in certain embodiments, administration of a compound of the invention to the subject removes or reduces the circulation concentration of the circulating protein or the autoantibody, thus treating, ameliorating, or preventing the disease and/or disorder. In certain embodiments, the circulating protein is TNF.

TRICYCLIC MODULATORS OF TNF SIGNALING

The invention provides tricyclic heterocyclic compounds, pharmaceutically acceptable salts, prodrugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variables are defined herein. The compounds of the invention may be useful for treating immunological and oncological conditions.

FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS

The present invention provides fused thiophene and thiazole derivatives of formula (I), which may be therapeutically useful, more particularly as RORγ modulators; in which R1, R2, R3, R4, R5, R6, R7, X1, X2, L, m, n and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in disease(s) or disorder(s) where there is an advantage in modulating RORγ receptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the fused thiophene and thiazole derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent or excipient therefor.