1420623-75-1

Upstream product

• 5469-70-5 3-aminopyridazine 
• 33142-21-1 ethyl 2-chloro-3-oxopropanoate 
• 1150566-27-0 6-chloroimidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester 
• 1428929-48-9 ethyl 2-bromo-3-(dimethylamino)-3-(pyridazin-3-ylamino)propanoate 
• 35053-54-4 N,N-dimethyl-N'-pyridazin-3-yl-formamidine 

Downstream Products

• 154578-27-5 imidazo[1,2-b]pyridazine-3-carbaldehyde 
• 1420623-06-8 C₂₄H₂₀ClN₅O 
• 1308384-58-8 imidazo[1,2-b]pyridazine-3-carboxylic acid 

Relevant academic research and scientific papers

Discovery of potent colony-stimulating factor 1 receptor inhibitors by replacement of hinge-binder moieties

Tumor-associated macrophages (TAMs) are predominantly associated with tumor growth. Colony-stimulating factor 1 receptor (CSF1R) acts as a key regulator of TAM survival and differentiation and is a molecular target for cancer therapies. Herein, novel CSF1

AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF

The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont

AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF

The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont

HETEROCYCLIC COMPOUNDS AND USES THEREOF

Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.