142066-06-6Relevant articles and documents
Dithio and Thiono Esters, 55. - Synthesis of N-Protected, Optically Active α-Amino Thiono Esters
Brutsche, Andreas,Hartke, Klaus
, p. 921 - 926 (2007/10/02)
The N-protected α-amino amides 1 are O-alkylated with trialkyloxonium tetrafluoroborates to form the iminium salts 2.Sulfhydrolysis of 2 yields the α-amino thiono esters 3.This reaction sequence allows the preparation of enantiomerically pure 3.Key Words: