24250-70-2

Usage

InChI:InChI=1/C10H12N2O2/c1-7(9(11)13)12-10(14)8-5-3-2-4-6-8/h2-7H,1H3,(H2,11,13)(H,12,14)

Upstream product

• 5446-46-8 ethyl 2-(benzoylamino)propanoate 
• 2198-64-3 N-Benzoylalanine 
• 51127-13-0 2-phenyl-4-methyl-4H-oxazolin-5-one 
• 60-29-7 diethyl ether 
• 7664-41-7 ammonia 
• 397851-05-7 N-Benzoylalanyl chloride 
• 7244-67-9 methyl N-benzoylalaninate 

Downstream Products

• 7244-67-9 methyl N-benzoylalaninate 
• 142066-06-6 N-Benzoyl-DL-thioalanin-O-ethylester 

Relevant academic research and scientific papers

Glycine-selective α-carbon-nitrogen bond cleavage of dipeptides by nickel peroxide

Nickel peroxide selectively cleaves the α-carbon-nitrogen bond of glycine residues in dipeptide derivatives to give the corresponding amides. The glycine selectivity is attributable to preferential complexation of the reactant residue to nickel peroxide and subsequent reaction via a stable α-centered glycyl radical. The oxidation process serves as a chemical model for peptidylglycine α-amidating monooxygenase (PAM) and, in addition, may have potential for the synthesis of α,β-didehydro amino acid residues within peptides.

Mild Conversion of Carboxamides and Carboxylic Acid Hydrazides to Acids and Esters

A mild and selective conversion of unsubstituted carboxamides and carboxylic acid hydrazides to the corresponding acids and esters is brought about by the use of acidic resins.Application of the procedure to several carboxamides and carboxylic acid hydrazides is described.