1420683-72-2Relevant academic research and scientific papers
Discovery of a highly potent, orally active mitosis/angiogenesis inhibitor R1530 for the treatment of solid tumors
Liu, Jin-Jun,Higgins, Brian,Ju, Grace,Kolinsky, Kenneth,Luk, Kin-Chun,Packman, Kathryn,Pizzolato, Giacomo,Ren, Yi,Thakkar, Kshitij,Tovar, Christian,Zhang, Zhuming,Wovkulich, Peter M.
, p. 259 - 263 (2013/04/10)
A new series of 7,8-disubstituted pyrazolobenzodiazepines based on the lead compound 1 have been synthesized and evaluated for their effects on mitosis and angiogenesis. Described herein is the design, synthesis, SAR, and antitumor activity of these compo
