142074-05-3

Upstream product

• 64064-25-1 2-Amino-5-(phenylthio)pyridin 
• 70-11-1 α-bromoacetophenone 
• 20511-12-0 2-amino-5-iodopyridine 
• 108-98-5 thiophenol 
• 61982-63-6 2-phenyl-6-iodoimidazo[1,2-a]pyridine 

Downstream Products

• 142074-07-5 6-benzamidomethyl-2-phenyl-6-phenylthioimidazol<1,2-a>pyridine 
• 142074-06-4 3-acetamodomethyl-2-phenyl-6-phenylthioimidazo<1,2-a>pyridine 

Relevant academic research and scientific papers

Use of ligand-free iron/copper cocatalyst for nitrogen and sulfur cross-coupling reaction with 6-iodoimidazo[1,2- a ]pyridine

A ligand-free cooperative bimetallic iron/copper catalysis system was found to introduce various azoles and thiols onto 6-iodoimidazo[1,2-a] pyridine. After optimization, the inexpensive, nontoxic, air-stable, and commercially available CuO and FeCl2

Imidazopyridazines. XII. Syntheses and Central Nervous System Activities of Some Substituted Imidazopyridazines and Related Imidazopyridines, Imidazopyrimidines and Imidazopyrazines

Syntheses are reported for some 6-chloro(alkoxy, alkylthio and phenylthio)-3-benzamidomethyl-(acetamidomethyl and methoxy)-2-arylimidazopyridines and some corresponding imidazo-pyridazines, imidazopyrimidines and imidazopyrazines.IC50 values (or percentage displacement) are reported and discussed for the displacement of 3H>diazepam from rat brain membrane by each of these compounds.The imidazopyridines were generally less potent than the imidazopyridazines but considerably more potent than the corresponding imidazopyrimidines or imidazopyrazines.Substitution of 2-aryl group by a 2-alkyl group in imidazopyridazines led to a significant loss of activity.