142121-95-7 Usage
Uses
Used in Pharmaceutical Industry:
TERT-BUTOXYCARBONYLAMINO-(3,4-DICHLORO-PHENYL)-ACETIC ACID is used as a reagent for the synthesis of amino acid derivatives and peptides, which are essential building blocks in the development of various pharmaceutical products. Its potential applications in the development of antibacterial and antitumor agents make it a valuable component in the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, TERT-BUTOXYCARBONYLAMINO-(3,4-DICHLORO-PHENYL)-ACETIC ACID is utilized in the production of crop protection agents. Its role in the synthesis of these agents contributes to the development of effective solutions for pest and disease control in agriculture, ensuring crop yield and quality.
Used in Chemical Synthesis:
TERT-BUTOXYCARBONYLAMINO-(3,4-DICHLORO-PHENYL)-ACETIC ACID is used as a key intermediate in the synthesis of diverse chemical compounds with various commercial applications. Its versatility in chemical reactions allows for the creation of a wide range of products, from pharmaceuticals to agrochemicals, highlighting its importance in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 142121-95-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,1,2 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 142121-95:
(8*1)+(7*4)+(6*2)+(5*1)+(4*2)+(3*1)+(2*9)+(1*5)=87
87 % 10 = 7
So 142121-95-7 is a valid CAS Registry Number.
142121-95-7Relevant academic research and scientific papers
Highly selective tripeptide thrombin inhibitors
Shuman,Rothenberger,Campbell,Smith,Gifford-Moore,Gesellchen
, p. 314 - 319 (2007/10/02)
Tripeptide aldehydes such as Boc-D-Phe-Pro-Arg-H (5l) exhibit potent direct inhibition of thrombin. This distinction offers important insight for the design of more potent and selective serine protease inhibitors which may be useful pharmacological tools and hold promise for development of clinically useful agents. The structure-activity relationships (SAR) on a series of anticoagulant peptides with high selectivity for the enzyme thrombin are discussed. The SAR is centered on a series of di- and tripeptide arginine aldehydes based on the structure of 5l. The structural and conformational role of the amino acid residue in position 1 was investigated by substitution with conformationally restricted aromatic amino acids, aromatic acids, and a dipeptide isostere containing the ψ[CH2N] amide bond replacement. Many of these peptides demonstrate potent antithrombotic activity along with selectivity toward thrombin, determined by comparison of in vitro inhibitory effects on trypsin, plasmin, factor Xa, and tissue plasminogen activator. Compound 5f, D-1-Tiq-Pro-Arg-H · sulfate is highly active and the most selective tripeptide aldehyde inhibitor of thrombin reported to date.
