1421236-78-3

Basic information

• Product Name: (R)-N-((1R,2R)-3-((S)-4-benzyl-5,5-dimethyl-2-oxooxazolidin-3-yl)-1-(5-fluoropyridin-2-yl)-2-methyl-3-oxopropyl)-2-methylpropane-2-sulfinamide
• Synonyms: (R)-N-((1R,2R)-3-((S)-4-benzyl-5,5-dimethyl-2-oxooxazolidin-3-yl)-1-(5-fluoropyridin-2-yl)-2-methyl-3-oxopropyl)-2-methylpropane-2-sulfinamide
• CAS NO: 1421236-78-3
• Molecular Weight: 489.611
• Mol File: 1421236-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-N-((1R,2R)-3-((S)-4-benzyl-5,5-dimethyl-2-oxooxazolidin-3-yl)-1-(5-fluoropyridin-2-yl)-2-methyl-3-oxopropyl)-2-methylpropane-2-sulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-((1R,2R)-3-((S)-4-benzyl-5,5-dimethyl-2-oxooxazolidin-3-yl)-1-(5-fluoropyridin-2-yl)-2-methyl-3-oxopropyl)-2-methylpropane-2-sulfinamide(1421236-78-3)
• EPA Substance Registry System: (R)-N-((1R,2R)-3-((S)-4-benzyl-5,5-dimethyl-2-oxooxazolidin-3-yl)-1-(5-fluoropyridin-2-yl)-2-methyl-3-oxopropyl)-2-methylpropane-2-sulfinamide(1421236-78-3)

Safety Data

• Hazardous Substances Data: 1421236-78-3(Hazardous Substances Data)

Upstream product

• 168297-85-6 (S)-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 1149752-50-0 (R,E)-N-((5-fluoropyridin-2-yl)methylene)-2-methylpropane-2-sulfinamide 
• 168297-93-6 (S)-4-benzyl-5,5-dimethyl-3-propanoyl-1,3-oxazolidin-2-one 
• 31181-88-1 5-fluoropicolinaldehyde 

Relevant articles and documents

Diastereoselective synthesis of β-heteroaryl syn -α-methyl- β-amino acid derivatives via a double chiral auxiliary approach

The addition of the SuperQuat enolate to five- and six-membered heterocyclic tert-butyl sulfinimines led to a high syn-selectivity of up to 99:1 in good to excellent yields. The reaction is tentatively proposed to proceed through an open-chain transition