1421252-48-3Relevant academic research and scientific papers
Method for inhibiting Trypanosoma cruzi
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Page/Page column 26; 27, (2016/09/26)
Methods are provided to inhibit proliferation of Trypanosoma cruzi with imido-substituted 1,4-naphthoquinones, including novel compounds. Administering an imido-substituted 1,4-naphthoquinone can be used to provide prophylaxis or treatment to a patient in
Synthesis and characterization of novel unsymmetrical and symmetrical 3-halo- or 3-methoxy-substituted 2-dibenzoylamino-1,4-naphthoquinone derivatives
Brandy, Yakini,Brandy, Nailah,Akinboye, Emmanuel,Lewis, Malik,Mouamba, Claudia,MacK, Seshat,Butcher, Ray J.,Anderson, Alan J.,Bakare, Oladapo
, p. 1973 - 1984 (2013/04/10)
Symmetrical and unsymmetrical 3-halo- or 3-methoxy- substituted 2-dibenzoylamino- 1,4-naphthoquinone analogs were synthesized with an average yield of 45% via sodium hydride promoted bis-acylation of 2-amino-3-chloro-1,4- naphthoquinone, 2-amino-3-bromo- 1,4-naphthoquinone and 2-amino-3-methoxy-1,4- naphthoquinone.
METHOD FOR INHIBITING TRYPANSOMA CRUZI
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Page/Page column 31; 32, (2013/03/26)
In its broadest aspect, a method for treating a mammalian patient at risk or suffering from a disease caused by a kinetoplastid parasite comprises administering to such subject an effective kinetoplasticidal amount of an imido-substituted 1,4- naphthoquin
