1421253-53-3

Upstream product

• 170033-47-3 (R)-tert-butyl 2-methylpiperazine-1-carboxylate 
• 1421253-19-1 (R)-tert-butyl 4-acetyl-2-methylpiperazine-1-carboxylate 
• 1421253-18-0 (R)-1-(3-methylpiperazin-1-yl)ethanone 2,2,2-trifluoroacetate 
• 98600-34-1 4-bromo-1H-indole-3-carbaldehyde 
• 1421254-71-8 4-bromo-3-methyl-1-tosyl-1H-indole 
• 475039-81-7 4-bromo-3-methyl-1H-indole 
• 1421252-96-1 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indole 
• 1421253-54-4 (R)-1-(4-(6-benzyl-2-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)-3-methylpiperazin-1-yl)ethanone 

Downstream Products

• 1421250-83-0 (R)-1-(3-methyl-4-(2-(3-methyl-1H-indol-4-yl)-6-(2-methyl-5-(3-methyloxetan-3-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)piperazin-1-yl)ethanone 
• 1421253-55-5 (R)-1-(3-methyl-4-(2-(3-methyl-1-tosyl-1H-indol-4-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)piperazin-1-yl)ethanone 
• 1421253-56-6 (R)-1-(3-methyl-4-(2-(3-methyl-1-tosyl-1H-indol-4-yl)-6-(2-methyl-5-(3-methyloxetan-3-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)piperazin-1-yl)ethanone 

Relevant academic research and scientific papers

TETRAHYDROPYRIDO-PYRIDINE AND TETRAHYDROPYRIDO-PYRIMIDINE COMPOUNDS AND USE THEREOF AS C5A RECEPTOR MODULATORS

The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.