1421314-76-2Relevant academic research and scientific papers
Carbamoyl pyridone HIV-1 integrase inhibitors. 2. Bi- and tricyclic derivatives result in superior antiviral and pharmacokinetic profiles
Kawasuji, Takashi,Johns, Brian A.,Yoshida, Hiroshi,Weatherhead, Jason G.,Akiyama, Toshiyuki,Taishi, Teruhiko,Taoda, Yoshiyuki,Mikamiyama-Iwata, Minako,Murai, Hitoshi,Kiyama, Ryuichi,Fuji, Masahiro,Tanimoto, Norihiko,Yoshinaga, Tomokazu,Seki, Takahiro,Kobayashi, Masanori,Sato, Akihiko,Garvey, Edward P.,Fujiwara, Tamio
, p. 1124 - 1135 (2013/03/28)
This work is a continuation of our initial discovery of a potent monocyclic carbamoyl pyridone human immunodeficiency virus type-1 (HIV-1) integrase inhibitor that displayed favorable antiviral and pharmacokinetic properties. We report herein a series of
