142134-07-4

Upstream product

• 142133-96-8 (2R)-2-(tert-Butyl)-6-trifluormethyl-2H,4H-1,3-dioxin-4-on 
• 142133-95-7 (2R,6R)-5-Bromo-2-tert-butyl-6-trifluoromethyl-[1,3]dioxan-4-one 
• 156593-89-4 (2R,5R,6R)-5-Brom-2-(tert-butyl)-6-trifluormethyl-1,3-dioxan-4-on 
• 131970-17-7 (2R,6S)-2-tert-Butyl-6-trifluoromethyl-[1,3]dioxan-4-one 
• 591-51-5 phenyllithium 

Downstream Products

• 75369-68-5 (R)-4,4,4-Trifluor-3-hydroxy-3-phenylbuttersaeure-methylester 
• 174135-96-7 (2R,3S)-methyl 2-amino-4,4,4-trifluoro-3-hydroxy-3-phenylbutanoate 

Relevant academic research and scientific papers

Preparation of Enantiomerically Pure 4,4,4-Trifluoro-3-hydroxy-butanoic Acid Derivatives, Branched in the 2- or 3-Position, from 6-Trifluoromethyl-1,3-dioxan- and -dioxin-4-ones

Enantiomerically pure 3-hydroxy-3-trifluoromethyl-propionic acid and esters, substituted in the 2- or 3-position, are prepared (13 examples) from (R)- or (S)-4,4,4-trifluoro-3-hydroxy-butanoic acid.Key intermediates are the 2-t-butyl-6-trifluoromethyl-1,3