75369-68-5Relevant academic research and scientific papers
Preparation of Enantiomerically Pure 4,4,4-Trifluoro-3-hydroxy-butanoic Acid Derivatives, Branched in the 2- or 3-Position, from 6-Trifluoromethyl-1,3-dioxan- and -dioxin-4-ones
Gautschi, Markus,Schweizer, W. Bernd,Seebach, Dieter
, p. 565 - 580 (2007/10/02)
Enantiomerically pure 3-hydroxy-3-trifluoromethyl-propionic acid and esters, substituted in the 2- or 3-position, are prepared (13 examples) from (R)- or (S)-4,4,4-trifluoro-3-hydroxy-butanoic acid.Key intermediates are the 2-t-butyl-6-trifluoromethyl-1,3
