1421353-67-4

Basic information

• Product Name: (2S,3S)-1-(4-chlorophenyl)-2,3-diphenyl-3-(tosylamino)propan-1-one
• Synonyms: (2S,3S)-1-(4-chlorophenyl)-2,3-diphenyl-3-(tosylamino)propan-1-one
• CAS NO: 1421353-67-4
• Molecular Weight: 490.022
• Mol File: 1421353-67-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-1-(4-chlorophenyl)-2,3-diphenyl-3-(tosylamino)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-1-(4-chlorophenyl)-2,3-diphenyl-3-(tosylamino)propan-1-one(1421353-67-4)
• EPA Substance Registry System: (2S,3S)-1-(4-chlorophenyl)-2,3-diphenyl-3-(tosylamino)propan-1-one(1421353-67-4)

Safety Data

• Hazardous Substances Data: 1421353-67-4(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 1889-71-0 4'-chloro-2-phenylacetophenone 

Relevant articles and documents

Highly enantioselective three-component direct mannich reactions of unfunctionalized ketones catalyzed by bifunctional organocatalysts

A highly stereoselective three-component direct Mannich reaction between aromatic aldehydes, p-toluenesulfonamide, and unfunctionalized ketones was achieved through an enolate mechanism for the first time with a bifunctional quinidine thiourea catalyst. The corresponding N-tosylated β-aminoketones were obtained in high yields and excellent diastereo- and enantioselectivities (up to >99:1 dr and >99% ee).