1421356-05-9Relevant academic research and scientific papers
One-Pot Highly Regioselective Synthesis of Indole-Fused Pyridazino[4,5- b ][1,4]benzoxazepin-4(3 H)-ones by a Smiles Rearrangement
Jiang, Xiaolei,Hu, Fangdong
supporting information, p. 1207 - 1210 (2018/03/23)
A simple and convenient synthesis of indole-fused pyridazino[4,5- b ][1,4]benzoxazepin-4(3 H)-ones is described. A range of 2-(1 H -indol-2-yl)phenols and 4,5-dichloropyridazin-3-ones are compatible with this reaction. A Smiles rearrangement is proposed as a key step in the highly regioselective construction of the products. The easy availability of the starting materials makes this an appealing method in organic synthesis.
Remote anionic fries rearrangement of sulfonates: Regioselective synthesis of indole triflones
Xu, Xiu-Hua,Taniguchi, Misaki,Azuma, Ayaka,Liu, Guo Kai,Tokunaga, Etsuko,Shibata, Norio
supporting information, p. 686 - 689 (2013/03/29)
An unusual NaH-mediated remote anionic 1,5-thia-Fries rearrangement reaction was developed. This method provides an efficient approach for the regioselective synthesis of not only 2-(2-hydroxyphenyl)-3-indole triflones but also related 3-sulfonylindoles.
