1421429-19-7Relevant articles and documents
Asymmetric intermolecular conjugate addition of amino acid derivatives via memory of chirality: Total synthesis of manzacidin A
Yoshimura, Tomoyuki,Kinoshita, Tomohiko,Yoshioka, Hiroyasu,Kawabata, Takeo
supporting information, p. 864 - 867 (2013/04/10)
Asymmetric intermolecular conjugate addition of α-amino acid derivatives with 4 via memory of chirality has been developed. The reactions proceeded in up to 98% ee with retention of configuration at the newly formed tetrasubstituted carbon center when R = Me. The product (R = Me) was transformed into manzacidin A.
