1421435-12-2

Basic information

• Product Name: 2-[2-(6-bromochroman-4-ylidene)hydrazinyl]-5-phenylthiazole
• CAS NO: 1421435-12-2
• Molecular Weight: 400.299
• Mol File: 1421435-12-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[2-(6-bromochroman-4-ylidene)hydrazinyl]-5-phenylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(6-bromochroman-4-ylidene)hydrazinyl]-5-phenylthiazole(1421435-12-2)
• EPA Substance Registry System: 2-[2-(6-bromochroman-4-ylidene)hydrazinyl]-5-phenylthiazole(1421435-12-2)

Safety Data

• Hazardous Substances Data: 1421435-12-2(Hazardous Substances Data)

Upstream product

• 3875-78-3 6-bromo-chroman 
• 79-19-6 thiosemicarbazide 
• 70-11-1 α-bromoacetophenone 
• 93670-18-9 3-(4-bromophenyloxy)-propionic acid 
• 106-41-2 4-bromo-phenol 

Relevant articles and documents

Synthesis and antifungal activity of some thiazole derivatives

A series of some thiazole derivatives were designed and synthesized. The structure of newly synthesized compounds was characterized by HRMS, 1H NMR and 13C NMR. The synthesized compounds were evaluated against ten species of fungi in vitro by agar cup plate and micro-titration methods, respectively. The results of antifungal screening reveal that among all the compounds screened three compounds showed moderate antifungal activity. The MIC value of 3 h against two fungal strains C. neoformans and C. albicas is 8 μg mL-1 respectively. The MIC value of 3i against two fungal strains C. neoformans and T. mentagrophytes is 8 μg mL-1 and 16 μg mL-1, respectively and 3a against T. mentagrophytes is 16 μg mL-1, the MIC of others are all beyond 32 μg mL-1.