3875-78-3

Usage

Uses

Used in Chemical Synthesis:
6-Bromo-chroman is used as a starting material in various chemical reactions due to its bromine atom substitution. This makes it a valuable intermediate in the synthesis of more complex organic compounds.
Used in Environmental Research:
6-Bromo-chroman is used in environmental studies to understand its interactions in processes such as halogen cycling and organic matter degradation. This helps in assessing its role and impact in environmental systems.
Used in Pharmaceutical Development:
6-Bromo-chroman may be used as a building block in the development of pharmaceutical compounds, leveraging its unique structure and reactivity for potential therapeutic applications.
Used in Material Science:
6-BROMO-CHROMAN's aromaticity and ring structure make it a candidate for use in the development of new materials with specific properties, such as in polymers or other advanced materials.

InChI:InChI=1/C9H9BrO/c10-8-3-4-9-7(6-8)2-1-5-11-9/h3-4,6H,1-2,5H2

Upstream product

• 56-23-5 tetrachloromethane 
• 128-08-5 N-Bromosuccinimide 
• 493-08-3 chromane 
• 94-36-0 dibenzoyl peroxide 
• 64010-38-4 1-bromo-4-(3-chloropropoxy)benzene 
• 57083-30-4 acetic acid-(2-allyl-4-bromo-phenyl ester) 
• 109210-20-0 6-bromo-3,4-dihydro-2H-1-benzopyran-2-ol 
• 7726-95-6 bromine 
• 67900-64-5 3-(4-Bromophenoxy)-1-propanol 
• 106-41-2 4-bromo-phenol 
• 7003-65-8 sodium 4-bromophenoxide 
• 65537-54-4 3-(3-bromophenyl)-propan-1-ol 
• 93670-18-9 3-(4-bromophenyloxy)-propionic acid 
• 3384-04-1 3-chloropropyl phenyl ether 

Downstream Products

• 1421435-12-2 2-[2-(6-bromochroman-4-ylidene)hydrazinyl]-5-phenylthiazole 
• 18385-77-8 6-bromo chroman-4-ol 
• 1002727-88-9 2-(chroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

Anthracene derivatives compounds and organic electroluminescent devices comprising the same

The present invention relates to a novel organic electroluminescent compound which is represented by the following [chemical formula 1] or [chemical formula 2]. The electroluminescent compound according to the present invention has high glass transition temperature, thereby having enhanced thermal stability; and can form an organic electroluminescent device having low driving voltage, high luminance, high color purity, and long-life when applying the same to the electroluminescent device.

Benzene C-H Etherification via Photocatalytic Hydrogen-Evolution Cross-Coupling Reaction

Aryl ethers can be constructed from the direct coupling between the benzene C-H bond and the alcohol O-H bond with the evolution of hydrogen via the synergistic merger of photocatalysis and cobalt catalysis. Utilizing the dual catalyst system consisting of 3-cyano-1-methylquinolinum photocatalyst and cobaloxime, intermolecular etherification of arenes with various alcohols and intramolecular alkoxylation of 3-phenylpropanols with formation of chromanes are accomplished. These reactions proceed at remarkably mild conditions, and the sole byproduct is equivalent hydrogen gas.

Synthesis and antifungal activity of some thiazole derivatives

A series of some thiazole derivatives were designed and synthesized. The structure of newly synthesized compounds was characterized by HRMS, 1H NMR and 13C NMR. The synthesized compounds were evaluated against ten species of fungi in vitro by agar cup plate and micro-titration methods, respectively. The results of antifungal screening reveal that among all the compounds screened three compounds showed moderate antifungal activity. The MIC value of 3 h against two fungal strains C. neoformans and C. albicas is 8 μg mL-1 respectively. The MIC value of 3i against two fungal strains C. neoformans and T. mentagrophytes is 8 μg mL-1 and 16 μg mL-1, respectively and 3a against T. mentagrophytes is 16 μg mL-1, the MIC of others are all beyond 32 μg mL-1.

N-phenpropylcuclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase

The invention relates to compounds of formula (I) for treating for example sexual dysfunction, wherein R1 is optionally substituted C1-6alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, hydrogen, C1-6alkoxy, —NR2 R3 or —NR4SO2R5; X is the linkage —(CH2)n— or —(CH2)q—O— (wherein Y is attached to the oxygen); wherein one or more hydrogen atoms in linkage X may be replaced independently by C1-4alkoxy; hydroxy; hydroxy(C1-3alkyl); C3-7cycloalkyl; carbocyclyl; heterocyclyl; or by C1-4alkyl optionally substituted by one or more fluoro or phenyl groups; n is 3, 4, 5, 6 or 7; and q is 2, 3, 4, 5 or 6; and Y is phenyl or pyridyl, each of which may be substituted; or two R8 groups on adjacent carbon atoms together with the interconnecting carbon atoms may form a fused optionally substituted 5- or 6-membered carbocyclic or heterocyclyic ring.

The Synthesis of Bridged Oligophenylenes from Fluorene 1. Terphenyls and Quaterphenyls

Improved methods are presented for the alkylation of fluorene (2) to 9,9- dialkylfluorenes (3-6) free from 9-monoalkylfluorenes.Mono- and dihalogenated derivatives of 2-6 are reported as are a variety of ring substituted 9,9-dialkylfluorenes.Halogenated 9,9-dialkylfluorenes and aryl or methyl Grignard reagents were cross-coupled in Pd-catalyzed reactions to generate a series of novel p-oligophenylenes (four terphenyls (26, 27, 29 and 31c) and nineteen quterphenyls (33-6, 64-71 and 73-79)) each possessing one or two dialkylated methylene bridges between aromatic rings.Each bridged oligophneylene showed enhanced solubility, high quantum efficiency and photochemical stability.A number of quaterphenyls incorporated substituents which extended the conjugation of the oligophenylene chromophore.

ACETYLATION, BROMINATION, AND NITRATION OF BENZOXAHETEROCYCLES AND SYNTHESIS OF β-AMINOKETONES FROM ACETYL DERIVATIVES

The method of competing reactions was used to establish the sequence of variation of the relative rates of acetylation, bromination, and nitration reactions of 2-methylcoumaran, chroman, 2,3,4,5-tetrahydrobenzo-1-oxepan, and 1-methoxy-2-ethylbenzene.The i