142148-77-4Relevant academic research and scientific papers
Design, synthesis and biological evaluation of selective boron-containing thrombin inhibitors
Wienand, Anette,Ehrhardt, Claus,Metternich, Rainer,Tapparelli, Carlo
, p. 1295 - 1307 (1999)
Based on the structural comparison of the S-1 pocket in different trypsin-like serine proteases, a series of Boc-D-trimethylsilylalanine-proline-boro-X pinanediol derivatives, with boro-X being different amino boronic acids, have been synthesised as inhib
Selective boron-containing thrombin inhibitors - X-ray analysis reveals surprising binding mode
Von Matt, Anette,Ehrhardt, Claus,Burkhard, Peter,Metternich, Rainer,Walkinshaw, Malcolm,Tapparelli, Carlo
, p. 2291 - 2303 (2000)
Based on the structural comparison of the S1 pocket in different trypsin-like serine proteases, a series of Boc-D-trimethylsilylalanine-proline-boro-X pinanediol derivatives, with boro-X being different amino boronic acids, have been synthesized as inhibi
