1421611-35-9

Basic information

• Product Name: 2-{2-[6-(6,8-dichloro-4-oxo-4H-quinazolin-3-yl)-pyrimidin-4-yloxy]phenyl}-3-methoxy-acrylic acid methyl ester
• CAS NO: 1421611-35-9
• Molecular Weight: 499.31
• Mol File: 1421611-35-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{2-[6-(6,8-dichloro-4-oxo-4H-quinazolin-3-yl)-pyrimidin-4-yloxy]phenyl}-3-methoxy-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[6-(6,8-dichloro-4-oxo-4H-quinazolin-3-yl)-pyrimidin-4-yloxy]phenyl}-3-methoxy-acrylic acid methyl ester(1421611-35-9)
• EPA Substance Registry System: 2-{2-[6-(6,8-dichloro-4-oxo-4H-quinazolin-3-yl)-pyrimidin-4-yloxy]phenyl}-3-methoxy-acrylic acid methyl ester(1421611-35-9)

Safety Data

• Hazardous Substances Data: 1421611-35-9(Hazardous Substances Data)

Upstream product

• 131860-97-4 (E)-methyl 2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxy-propenoate 
• 6952-11-0 6,8-dichloroquinazolin-4(3H)-one 

Relevant articles and documents

Synthesis of novel quinazolinone derivatives with methyl (E)-2-(3-methoxy)acrylate moiety

A new series of quinazolinone derivatives with methyl (E)-2-(3-methoxy) acrylate moiety have been designed and synthesized. All target compounds had been identified by 1H NMR spectrum, IR spectrum and HR-MS (high resolution mass spectrum). Three target compounds (10a, 10e, 10h) were chosen to preliminarily test the antibacterial activities, the results showed that all three target compounds exhibited antibacterial activities against three bacterial strains (Proteobacteria, Salmonella, Colibacillus).