131860-97-4Relevant articles and documents
Preparation method of azoxystrobin intermediate
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Paragraph 0041-0058, (2021/08/06)
The invention relates to the technical field of preparation of pesticide intermediates, in particular to a preparation method of an azoxystrobin intermediate. The invention relates to a preparation method of an azoxystrobin intermediate, which comprises the following steps: putting methoxymethylene benzofuranone and dichloropyrimidine into a solvent, adding alkali and a catalyst to carry out ring-opening reaction, adding alkali again, and carrying out etherification reaction to synthesize an azoxystrobin intermediate compound (E)-2-[2-(6-chloropyrimidine-4-methoxy) phenyl]-3methoxy methyl acrylate C; the reaction formula is disclosed in the invention; the structural formula of the catalyst is selected from any one disclosed in the invention; according to the invention, reaction is selectively carried out on the ring opening of methoxymethylene benzofuranone, Michael addition is inhibited, the generation of by-products B is reduced, and the problem of low efficiency of catalysts such asDABCO, trimethylamine and the like is solved at the same time.
PROCESS FOR PREPARATION OF AZOXYSTROBIN AND INTERMEDIATES THEREOF
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Page/Page column 29-30, (2020/10/27)
The present invention relates to a process for preparation of strobilurin compound, azoxystrobin and its intermediates using a catalyst selected from 1,8-Diazabicyclo[5.4.0]undec-7-ene or 1,5-Diazabicyclo[4.3.0]non-5-ene, salts thereof, or derivatives thereof.
Preparation method of azoxystrobin compound
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Paragraph 0061-0066, (2019/12/02)
The present invention relates to the field of chemical synthesis, and discloses a preparation method of azoxystrobin compounds, which comprises steps that a compound represented by a formula (II) is adopted as a raw material to carry out a reaction, wherein R is halogen, a hydroxyl group or a 2-cyanophenoxy group. According to the method disclosed by the invention, the pure azoxystrobin compound can be simply and conveniently obtained, a complex separation and purification process is avoided, the waste of raw materials is reduced, and the atom utilization rate is improved.