14217-66-4 Usage
General Description
3-Chloroisothiazole is a chemical compound with the molecular formula C3H2ClNS. It is a heterocyclic compound containing a five-membered ring with a chlorine atom attached at the third position. 3-Chloroisothiazole is widely used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active compounds. It serves as a versatile intermediate in the production of drugs, herbicides, and pesticides. Due to its strong nucleophilic nature, it can undergo various chemical reactions such as nucleophilic substitution, cyclization, and condensation to yield different derivatives with diverse applications. Overall, 3-Chloroisothiazole plays a crucial role in the synthesis of important pharmaceutical and agricultural products.
Check Digit Verification of cas no
The CAS Registry Mumber 14217-66-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,1 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 14217-66:
(7*1)+(6*4)+(5*2)+(4*1)+(3*7)+(2*6)+(1*6)=84
84 % 10 = 4
So 14217-66-4 is a valid CAS Registry Number.
14217-66-4Relevant articles and documents
A 3 - chloroisothiazole chemical synthesis method
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Paragraph 0023; 0024, (2018/02/22)
The invention relates to a chemical synthesis method of 3-chloroisothiazole. The chemical synthesis method takes 4,5- dithio-1,8-octanedioic acid as a material and simply synthesizes 3-chloroisothiazole by two-step reaction. The method is as follows: adding the 4,5- dithio-1,8-octanedioic acid into thionyl chloride, evaporating out thionyl chloride after reaction is ended, adding into ammonia water, controlling a temperature to generate 4,5- dithio-1,8-octanedioyl amine; dissolving phosphorus oxychloride in an organic solvent toluene, adding 4,5- dithio-1,8-octanedioyl amine, controlling the reaction temperature at a lower temperature, increasing the temperature for reaction after reacting for 48 hours to synthesize 3-chloroisothiazole. The chemical synthesis method disclosed by the invention is low in synthesis route cost, high in yield, simple and convenient to operate, and therefore, an efficient synthesis method is provided for synthesizing the compound.
