1421708-29-3

Upstream product

• 112897-97-9 (E)-3-(3,4-difluorophenyl)acrylic acid 
• 376608-66-1 (E)-3-(3,4-difluorophenyl)acryloyl chloride 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1334528-90-3 (E)-3-(3,4-difluorophenyl)acrylaldehyde 
• 1156491-10-9 trans-2-(3,4-difluorophenyl)cyclopropanamine hydrochloride 
• 1006614-49-8 trans-2-(3,4-difluorophenyl)cyclopropanamine 
• 376608-71-8 trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropylamine (2R)-2-hydroxy-2-phenylacetic acid salt 
• 1006614-50-1 trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 

Relevant academic research and scientific papers

SYNTHESIS OF 2-(3,4-DIFLUOROPHENYL)CYCLOPROPANAMINE DERIVATIVES AND SALTS

The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

NOVEL SPIROINDOLINE COMPOUNDS

This invention relates to novel spiroindoline compounds of formula (I) that are generally useful as medicaments, more specifically as medicaments for animals. The medicament can preferably be used for the treatment of helminth infections and the treatment of parasitosis, such as caused by helminth infections. This invention also relates to uses of the compounds to make medicaments and treatments comprising the administration of the compounds to animals in need of the treatments. This invention also relates to the preparation of said compounds. Moreover this invention relates to pharmaceutical compositions and kits comprising the compounds.