142176-75-8

Upstream product

• 142176-95-2 (R)-1-Benzyloxy-6-trimethylsilanyl-hex-4-yn-2-ol 
• 917-54-4 methyllithium 
• 337983-98-9 (R)-7-benzyloxymethyl-2,2-dimethyl-2,3,6,7-tetrahydro-[1,2]oxasilepine 
• 58931-16-1 (R)-1-benzyloxypent-4-en-2-ol 
• 14618-80-5 (R)-benzyl glycidol 
• 337983-96-7 Allyl-((R)-1-benzyloxymethyl-but-3-enyloxy)-dimethyl-silane 
• 13361-64-3 trimethyl(propargyl)silane 

Downstream Products

• 112497-21-9 (4S,6S)-6-<(benzyloxy)methyl>-4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxacyclohexane 
• 106799-17-1 (2R)-1-(benzyloxy)-5-hexene-2,4-diol 
• 114925-52-9 <4R-(4α,5α)>-4-<(phenylmethoxy)methyl>-6-ethenyl-2,2-dimethyl-1,3-dioxane 
• 534584-66-2 (1R,2R)-2-((benzyloxy)methyl)cyclopropanecarbaldehyde 
• 142096-80-8 (-)-(1R,2R)-2-benzyloxymethyl-1-hydroxymethylcyclopropane 
• 52745-75-2 (-)-(1R,3R)-1,3-bis(hydroxymethyl)cyclopropane 
• 188610-46-0 1-((((1R,2S)-2-vinylcyclopropyl)methoxy)methyl)benzene 

Relevant academic research and scientific papers

Synthetic methodology for the construction of structurally diverse cyclopropanes

Practical and efficient routes for the stereoselective conversion of homoallylic alchols to diastereomerically pure cis-, trans-1,2-disubstituted, and 1,2,3-trisubstituted cyclopropanes have been developed. The routes are highlighted by olefin metathesis

Stereoselective synthesis of syn1,3-diols

Z-allylsilanes 1 are epoxidized by V5+/TBHP with high erythro-selectivity (up to 97:3). HF- or TBAFinduced fragmentation leads to syn-l,3-diols 3. Compound 3f can be gtransformed within two steps into a key synthon for the lactone moiety of com