114925-52-9

Upstream product

• 106799-17-1 (2R)-1-(benzyloxy)-5-hexene-2,4-diol 
• 77-76-9 2,2-dimethoxy-propane 
• 106799-17-1 (2R,4S)-1-<(phenylmethoxy)methyl>5-hexene-2,4-diol 
• 100-39-0 benzyl bromide 
• 41546-31-0 L-xylose 
• 114861-37-9 3-deoxy-5-O-(phenylmethyl)-α-L-xylofuranose 
• 106799-16-0 tert-Butyl-((3aS,5R,6aS)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-diphenyl-silane 
• 220827-73-6 5-O-tert-butyldiphenylsilyl-1,2-O-isopropylidene-α-L-xylofuranose 
• 114861-15-3 Thiocarbonic acid O-[(3aS,5S,6R,6aS)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl] ester O-phenyl ester 
• 142176-75-8 (Z)-(R)-1-benzyloxy-6-(trimethyl-silanyl)-hex-4-en-2-ol 
• 142176-95-2 (R)-1-Benzyloxy-6-trimethylsilanyl-hex-4-yn-2-ol 
• 14618-80-5 (R)-benzyl glycidol 
• 114861-22-2 1,2-O-isopropylidene-α-L-xylofuranose 
• 114861-24-4 3-deoxy-1,2-O-(1-methylethylidene)-5-O-(phenylmethyl)-α-L-xylofuranose 

Downstream Products

• 106799-18-2 3,5-dideoxy-6-O-<(1,1-dimethylethyl)dimethylsilyl>-2,4-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-erythro-hexitol 
• 114925-53-0 3,5-dideoxy-2,4-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-erythro-hexitol 
• 112497-21-9 (4S,6S)-6-<(benzyloxy)methyl>-4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxacyclohexane 

Relevant academic research and scientific papers

Stereoselective synthesis of syn1,3-diols

Z-allylsilanes 1 are epoxidized by V5+/TBHP with high erythro-selectivity (up to 97:3). HF- or TBAFinduced fragmentation leads to syn-l,3-diols 3. Compound 3f can be gtransformed within two steps into a key synthon for the lactone moiety of com

Total Synthesis of Amphoteronolide B and Amphotericin B. 1. Strategy and Stereocontrolled Construction of Key Building Blocks

The retrosynthetic analysis and strategy for the total synthesis of amphotericin B (1) and amphoteronolide B (2) is discussed.Focusing on subtle and repeated structural units, a retrosynthetic scheme was constructed that led to the recognition of readily