1421851-02-6

Basic information

• Product Name: 2,2,2-trichloro-N-((1R)-6-(dimethoxymethyl)-4-methyl-2-oxo-1-vinylcyclohex-3-en-1-yl)acetamide
• Synonyms: 2,2,2-trichloro-N-((1R)-6-(dimethoxymethyl)-4-methyl-2-oxo-1-vinylcyclohex-3-en-1-yl)acetamide
• CAS NO: 1421851-02-6
• Molecular Weight: 370.66
• Mol File: 1421851-02-6.mol

Chemical Properties

• CAS DataBase Reference: 2,2,2-trichloro-N-((1R)-6-(dimethoxymethyl)-4-methyl-2-oxo-1-vinylcyclohex-3-en-1-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trichloro-N-((1R)-6-(dimethoxymethyl)-4-methyl-2-oxo-1-vinylcyclohex-3-en-1-yl)acetamide(1421851-02-6)
• EPA Substance Registry System: 2,2,2-trichloro-N-((1R)-6-(dimethoxymethyl)-4-methyl-2-oxo-1-vinylcyclohex-3-en-1-yl)acetamide(1421851-02-6)

Safety Data

• Hazardous Substances Data: 1421851-02-6(Hazardous Substances Data)

Upstream product

• 149-73-5 trimethyl orthoformate 
• 271256-59-8 2,2,2-Trichloro-N-[(1R,6S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-2-oxo-1-vinyl-cyclohex-3-enyl]-acetamide 

Downstream Products

• 1421851-09-3 C₂₀H₂₂Cl₃NO₇ 
• 1421851-10-6 C₂₀H₂₂Cl₃NO₇ 
• 1421851-14-0 C₂₉H₄₁N⁽¹⁵⁾N₂O₁₀ 
• 1421851-03-7 2,2,2-trichloro-N-((1R,2R)-6-(dimethoxymethyl)-2-hydroxy-4-methyl-1-vinylcyclohex-3-en-1-yl)acetamide 
• 1421851-05-9 N-((1R,2S,3R,6S)-2-(benzyloxy)-4-(dimethoxymethyl)-6-methyl-3-vinyl-7-oxabicyclo[4.1.0]heptan-3-yl)-2,2,2-trichloroacetamide 
• 1421851-06-0 N-((1R,2S,3R,6S)-2-(benzyloxy)-4-(dimethoxymethyl)-3-formyl-6-methyl-7-oxabicyclo[4.1.0]heptan-3-yl)-2,2,2-trichloroacetamide 
• 1421851-18-4 C₂₅H₃₄Cl₃NO₆Si 
• 1421851-07-1 (1R)-1-((1R,2S,3S,6S)-2-(benzyloxy)-4-(dimethoxymethyl)-6-methyl-3-(2,2,2-trichloroacetamido)-7-oxabicyclo[4.1.0]heptan-3-yl)prop-2-yn-1-yl acetate 
• 352670-32-7 (1S,4S,5R,6S,8S,9S)-9-(benzyloxy)-6-(dimethoxymethyl)-8-hydroxy-8-methyl-3-oxo-5-(2,2,2-trichloroacetamido)-2-oxabicyclo[3.3.1]nonan-4-yl acetate 

Relevant articles and documents

An improved synthesis of (-)-5,11-dideoxytetrodotoxin

We describe an improved synthesis of (-)-5,11-dideoxytetrodotoxin from an enone, which was used for synthesis of tetrodotoxin and its analogues in this laboratory. One of the major modifications was to establish a two-step guanidinylation of trichloroacetamide of a highly functionalized intermediate, which allowed us to prepare 15N2-labeled 5,11-dideoxytetrodotoxin for biosynthetic investigations.