271256-59-8

Upstream product

• 253674-40-7 2,2,2-Trichloro-N-[(1R,2S,4S,5S)-4,5-dibromo-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-methyl-1-vinyl-cyclohexyl]-acetamide 
• 253674-41-8 (3aR,4S,7aS)-4-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-methyl-2-trichloromethyl-3a-vinyl-3a,4,5,7a-tetrahydro-benzooxazole 
• 162089-64-7 (1S,6S,1'S)-trichloro-N-[1-vinyl-4-methyl-6-(3',3'-dimethyl-2',4'-dioxolanyl)-cyclohex-3-enyl]acetamide 
• 253674-42-9 2,2,2-Trichloro-N-[(1R,2S,6S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-4-methyl-1-vinyl-cyclohex-3-enyl]-acetamide 

Downstream Products

• 253674-39-4 2,2,2-Trichloro-N-[(1R,2R,6S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-4-methyl-1-vinyl-cyclohex-3-enyl]-acetamide 
• 253674-42-9 2,2,2-Trichloro-N-[(1R,2S,6S)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-4-methyl-1-vinyl-cyclohex-3-enyl]-acetamide 
• 1421851-07-1 (1R)-1-((1R,2S,3S,6S)-2-(benzyloxy)-4-(dimethoxymethyl)-6-methyl-3-(2,2,2-trichloroacetamido)-7-oxabicyclo[4.1.0]heptan-3-yl)prop-2-yn-1-yl acetate 
• 1421851-18-4 C₂₅H₃₄Cl₃NO₆Si 
• 1421851-06-0 N-((1R,2S,3R,6S)-2-(benzyloxy)-4-(dimethoxymethyl)-3-formyl-6-methyl-7-oxabicyclo[4.1.0]heptan-3-yl)-2,2,2-trichloroacetamide 
• 1421851-05-9 N-((1R,2S,3R,6S)-2-(benzyloxy)-4-(dimethoxymethyl)-6-methyl-3-vinyl-7-oxabicyclo[4.1.0]heptan-3-yl)-2,2,2-trichloroacetamide 
• 1421851-03-7 2,2,2-trichloro-N-((1R,2R)-6-(dimethoxymethyl)-2-hydroxy-4-methyl-1-vinylcyclohex-3-en-1-yl)acetamide 
• 1421851-02-6 2,2,2-trichloro-N-((1R)-6-(dimethoxymethyl)-4-methyl-2-oxo-1-vinylcyclohex-3-en-1-yl)acetamide 
• 1421851-09-3 C₂₀H₂₂Cl₃NO₇ 
• 1421851-10-6 C₂₀H₂₂Cl₃NO₇ 
• 1421851-08-2 (1S,4S,4aR,5S,6R,7R,8aS)-5-(benzyloxy)-6-hydroxy-1,7-dimethoxy-7-methyl-3-oxo-4a-(2,2,2-trichloroacetamido)octahydro-1H-isochromen-4-yl acetate 
• 352670-29-2 1-Benzyl-3-[(1S,4S,5S,6S,8S,9S)-9-benzyloxy-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4,8-dihydroxy-8-methyl-3-oxo-2-oxa-bicyclo[3.3.1]non-5-yl]-urea 
• 352670-30-5 C₂₅H₂₆N₂O₆ 
• 253674-52-1 Acetic acid (1S,4S,6R,7S,8R,9S,10S)-8-(N'-acetyl-N',N''-dibenzyl-guanidino)-9-benzyloxy-6-methoxy-10-methyl-3-oxo-2,5-dioxa-tricyclo[5.2.2.0^4,8]undec-10-yl ester 

Relevant academic research and scientific papers

Stereocontrolled synthesis of (-)-5,11-dideoxytetrodotoxin

Asymmetric synthesis of (-)-5,11-dideoxytetrodotoxin, an analog of puffer fish toxin, was accomplished from a common key intermediate through a novel hydroxylation at the C-8 position with neighboring group participation of trichloroacetamide, a highly st

Stereocontrolled synthesis of (-)-5,11-dideoxytetrodotoxin

New derivatives of an intriguing marine natural product are now accessible. The first asymmetric synthesis of the simple tetrodotoxin analogue, 5,11-dideoxytetrodotoxin (3), was achieved. Hydroxylation at position C8 of the key intermediate 1 relied on th