1421914-31-9

Upstream product

• 4801-14-3 3,3-diphenylprop-2-en-1-ol 
• 1083314-76-4 C₂₂H₂₀S 
• 119-61-9 benzophenone 
• 17792-17-5 ethyl 3,3-diphenylacrylate 
• 98-59-9 p-toluenesulfonyl chloride 
• 3923-51-1 1,1-diphenylprop-2-en-1-ol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 536-57-2 p-toluene sulfinic acid 

Downstream Products

• 1421914-11-5 8-(4,4-diphenylbuta-1,3-dien-1-ylidene)-1,4-dioxaspiro[4.5]decane 
• 1170-03-2 1,2-diphenyl-3-tosylpropan-1-one 
• 1430110-72-7 1,1-bis(ethoxymethyl)-3-(3,3-diphenylallylidene)cyclobutane 

Relevant academic research and scientific papers

Water-Promoted Dehydrative Tsuji–Trost Reaction of Non-Derivatized Allylic Alcohols with Sulfinic Acids

A mild, green and extra activator-free synthesis of allylic sulfones from non-derivatized allylic alcohols and sulfinic acids was developed and only the easily-available Pd(PPh3)4 was used as the catalyst. This new method could be easily scaled up to gram scale, affording the target allylic sulfones in a nearly quantitative yield with water as the sole by-product. Mechanism studies both by various NMR techniques and by theoretical calculations suggested two reaction pathways may be involved in the reaction, which are dependent on the reaction media, that is, an eight-membered ring binding species may be formed in aqueous media between allylic alcohol, sulfinic acid and water, while a six-membered ring binding species may be formed in common aprotic organic solvent between allylic alcohol and sulfinic acid. Both binding species may be accounted for the efficient activation of allylic alcohols via hydrogen bonding.

Synthetic method for allyl sulfone

The invention belongs to the field of organic synthesis, and especially relates to a synthetic method for allyl sulfone. The synthetic method for allyl sulfone is provided. Protonic acid can be simultaneously added as an additive under the catalysis of a

One-Pot Synthesis of Allylic Sulfones, Ketosulfones, and Triflyl Allylic Alcohols from Domino Reactions of Allylic Alcohols with Sulfinic Acid under Metal-Free Conditions

A metal-free tandem procedure by using a sulfonylation reaction of aryl allylic alcohols followed by an iodobenzenediacetate (PIDA)-promoted oxidative functionalization has been established. Allylic sulfones, γ-ketosulfones, and triflyl allylic alcohols have been constructed in a single operation. The methodology incorporates the sulfonyl (both aryl and triflyl) functionality with a simple work-up procedure.

Coupling reaction of magnesium alkylidene carbenoids with α-sulfonylallyllithiums: An efficient route to multi-substituted vinylallenes

A variety of vinylallenes were successfully synthesized from 1-chlorovinyl p-tolyl sulfoxides and allyl or vinyl sulfones. Allyl and vinyl sulfones served as α-sulfonylallyllithium sources were prepared from carbonyl compounds in three or four steps in good overall yields. The coupling reaction of α-sulfonylallyllithiums with magnesium alkylidene carbenoids, which were generated from 1-chlorovinyl p-tolyl sulfoxides and isopropylmagnesium chloride, afforded multi-substituted vinylallenes in up to 88% yield. Georg Thieme Verlag KG Stuttgart · New York.